As always, you should consult with your healthcare provider about your specific health needs. Stacy Wiegman, PharmD. Both Micardis telmisartan and Micardis HCT are prescribed to treat high blood pressure, or hypertension, but they differ in the way they work.
Micardis is an angiotensin II blocker ARB that works by blocking the action of hormones in blood vessels that cause them to constrict. Micardis HCT does the same thing, but it also contains hydrochlorothiazide, a diuretic water pill that also helps lower blood pressure by increasing the excretion of sodium from your body.
Continue Learning about Antihypertensive What should I know before taking beta blockers? Keep each tablet in its blister pack until you are ready to take it. Gently push the tablet through the foil to remove it. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, this medicine can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. If you also take cholestyramine or colestipol, avoid taking these medications within 4 hours before or 4 hours after you take hydrochlorothiazide and telmisartan.
This list is not complete. Other drugs may affect hydrochlorothiazide and telmisartan, including prescription and over-the-counter medicines, vitamins, and herbal products.
Not all possible drug interactions are listed here. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.
Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. The renin-aldosterone link is mediated by angiotensin II, so co-administration of an ARB tends to reverse the potassium loss associated with these diuretics.
The mechanism of the antihypertensive effect of thiazides is not fully understood. Adverse effects associated with the use of MicardisPlus may include, but are not limited to, the following:.
Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. Clinical trials involving more than 2, patients were conducted to test the effects of telmisartan and hydrochlorothiazide in combination for the treatment of hypertension.
One factorial trial was included where patients were given combinations of telmisartan 20, 40, 80, mg or placebo and hydrochlorothiazide 6. For patients who did not experience adequate control of their condition with the randomized monotherapy dose or had not achieved adequate response after completing the up-titration of telmisartan, four other studies were held of at least six months duration which allowed the add-on of hydrochlorothiazide.
In active controlled studies, the addition of Lundbeck Takeda Pharmaceuticals U. Currently Enrolling Trials Show More.
0コメント